Evidence-Based with Doublebase

“Adherence to an emollient regimen has the potential to reduce the need for more expensive treatments and associated GP consultations.” 1

The Doublebase range of emollients can help optimise emollient therapy by offering an evidence-based choice of effective emollients that are well tolerated and that patients like to use.

Proven efficacy

Doublebase Gel 

  • An original gel formulation specially formulated to have the emolliency of an ointment but with the cosmetic acceptability of a cream.
  • Very efficient at rehydrating dry skin and outperformed two other proprietary emollients.2  

Doublebase DAYLEVE Gel 

  • Doublebase DAYLEVE Gel achieved significantly longer lasting and cumulative skin hydration when compared with established comparator creams when used twice daily.3, 4

Patient acceptability

Doublebase Gel 

  • Well tolerated by patients and has over 15 years of trusted use. 
  • In a blinded study, children who were empowered/allowed to select their own emollient were most likely to select Doublebase Gel from a selection of 7 different emollients.5

Doublebase DAYLEVE Gel 

  • Overall product acceptability and patients’ willingness to use the emollient again were significantly greater for Doublebase DAYLEVE Gel compared with a marketed emollient cream.3

Patient education

  • Dermal offers an extensive educational support programme to help Healthcare Professionals empower patients in the management of their skin conditions.

For example, EmolliZoo is a non-promotional child friendly mobile app, developed by Dermal, to help educate children about their emollients.


1. National Institute for Health and Care Excellence (2007). Atopic eczema in children: management of atopic eczema in children from birth up to the age of 12 years (CG57). London: National Institute for Health and Care Excellence.
2. Wynne A et al. An effective, cosmetically acceptable, novel hydro-gel emollient for the management of dry skin conditions. Journal of Dermatological Treatment 2002;13(2):61-66. [PDF]
3. Djokic-Gallagher J., Rosher P., Walker J., Sykes K. & Hart V. (2016). Emollient efficacy and acceptability in the treatment of eczematous dry skin: A double-blind, randomised comparison of two UK-marketed products. Journal of Dermatological Treatment. [Link]
4. Djokic-Gallagher J., Rosher P., Oliveira G. & Walker J. A Double-Blind, Randomised Study Comparing the Skin Hydration and Acceptability of Two Emollient Products in Atopic Eczema Patients with Dry Skin. Dermatol Ther (Heidelb). 2017. [Link]
5. Aslam A. Empowering children to select their own emollients. Dermatological Nursing 2009;8(4):1-5.